Shubich M G, Lopunova Zh K, Shul'zhenko V I
Arkh Patol. 1976;38(12):32-5.
Mast cells of hemangiomas localized in the skin and in the mucous membrane of the oral cavity, have a similar histochemical characteristics of protein and carbohydrate components. The histochemical characteristics of the carbohydrate component indicate either a high (as compared with the norm) degree of sulfating of heparin molecules, or quantitative accumulation of its molecules in the mast cells cytoplasm. Moreover, in mast cells there were revealed protein and a neutral carbohydrate component. An assumption is put forward that histochemical changes in mast cells in hemangiomas were of compensatory-adaptive character and were directed to prevent the thrombogenesis in hemangiomas.
位于皮肤和口腔黏膜的血管瘤中的肥大细胞，在蛋白质和碳水化合物成分方面具有相似的组织化学特征。碳水化合物成分的组织化学特征表明，要么肝素分子的硫酸化程度较高（与正常情况相比），要么其分子在肥大细胞胞质中定量积累。此外，在肥大细胞中还发现了蛋白质和中性碳水化合物成分。有人提出一种假设，即血管瘤中肥大细胞的组织化学变化具有代偿适应性特征，旨在防止血管瘤内血栓形成。
