梭形细胞血管瘤：1例口腔病损报告
Spindle cell hemangioma: report of a case presenting in the oral cavity.
作者信息
Sheehan Michael, Roumpf Sheila O, Summerlin Don-John, Billings Steven D
机构信息
Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 West 11th Street, Indianapolis, IN 46202, USA.
出版信息
J Cutan Pathol. 2007 Oct;34(10):797-800. doi: 10.1111/j.1600-0560.2006.00708.x.
BACKGROUND
Spindle cell hemangioma, formerly termed spindle cell hemangioendothelioma, is an uncommon benign vascular tumor. Presentation in the oral cavity is rare with only two previously reported cases.
METHODS
We report a case of spindle cell hemangioma that presented as an asymptomatic mass of the buccal mucosa in a 44-year-old man.
RESULTS
The tumor was a well-circumscribed vascular proliferation of spindled to epithelioid endothelial cells. Tumor cells with intracytoplasmic vascular lumens were present in several areas. Larger, ectatic, thin-walled vessels lined by a single layer of flattened endothelial cells were evident at the periphery and focally in more cellular areas. The tumor was positive for CD31 and CD34.
CONCLUSIONS
Spindle cell hemangioma rarely presents in the oral cavity and needs to be considered in the differential diagnosis of oral cavity vascular tumors to avoid misdiagnosis as a more aggressive vascular tumor.
背景
梭形细胞血管瘤，以前称为梭形细胞血管内皮瘤，是一种罕见的良性血管肿瘤。在口腔中出现的情况很少见，此前仅有两例报道。
方法
我们报告一例梭形细胞血管瘤病例，该病例表现为一名44岁男性颊黏膜的无症状肿块。
结果
肿瘤为界限清楚的由梭形至上皮样内皮细胞构成的血管增生。在几个区域可见有胞质内血管腔的肿瘤细胞。在周边以及在更多细胞区域的局灶性部位，可见由单层扁平内皮细胞衬里的较大、扩张的薄壁血管。肿瘤CD31和CD34呈阳性。
结论
梭形细胞血管瘤很少出现在口腔，在口腔血管肿瘤的鉴别诊断中需要考虑到，以避免误诊为更具侵袭性的血管肿瘤。
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