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将对杜氏旋毛虫感染的免疫力从免疫小鼠被动转移至其后代。

Passive transfer of immunity to infection with Nematospiroides dubius from immunised mice to their offspring.

作者信息

Chaicumpa V, Jenkin C R, Rowley D

出版信息

Aust J Exp Biol Med Sci. 1976 Jun;54(3):245-52. doi: 10.1038/icb.1976.25.

Abstract

The results given below show that, whilst it is not possible to transfer immunity to infections with Nematospiroides dubius passively with serum from immune mice to normal adult mice, young born to immune females are resistant to this infection. The immunity is dependent on an intake of immunoglobulin via the milk for a period longer than 24 h. The passive transfer of immunity from immune mothers to neonatal mice does not appear to be dependent on a specific class of immunoglobulins.

摘要

以下结果表明,虽然无法通过将免疫小鼠的血清被动转移给正常成年小鼠来使其获得对杜氏丝状线虫感染的免疫力,但免疫雌性所生的幼崽对这种感染具有抗性。这种免疫力依赖于通过乳汁摄入免疫球蛋白超过24小时。免疫母亲向新生小鼠的免疫被动转移似乎并不依赖于特定类别的免疫球蛋白。

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