犬（犬属家犬）血红蛋白α链的多个结构基因。

Multiple structural genes for the alpha chain of canine (Canis familiaris) hemoglobin.

作者信息

Dresler S L, Brimhall B, Jones R T

出版信息

Biochem Genet. 1976 Dec;14(11-12):1065-70. doi: 10.1007/BF00485137.

Abstract

There are two forms of the alpha chain of canine hemoglobin differing only at residue 130. One form (taualpha) contains threonine at this position, the other (Aalpha) contains alanine. Studies of two Labrador dog families strongly support the existance of multiple alpha-chain structural genes as the basis of the alpha-chain heterogeneity. There must be at least one gene locus for Talpha and one for Aalpha; the exact number of loci has not been determined. Two other dog breeds, the Basenji and the Beagle, also have both Talpha and Aalpha chains.

摘要

犬血红蛋白α链有两种形式，仅在第130位残基处不同。一种形式（τ-α）在该位置含有苏氨酸，另一种（A-α）含有丙氨酸。对两个拉布拉多犬家族的研究有力地支持了多个α链结构基因的存在是α链异质性的基础。T-α至少必须有一个基因座，A-α也至少有一个基因座；基因座的确切数量尚未确定。另外两个犬种，巴仙吉犬和比格犬，也同时拥有T-α链和A-α链。