Berezkin M V
Biull Eksp Biol Med. 1976;82(11):1363-5.
Circadian rhythm of cell division in the forestomack epithelium proved to be largely similar to that in the transplantable (continuous) carcinoma of the forestomack; the duration of mitosis in these tissues changed in the course of 24-hours. The mean 24-hour mitotic activity in the tumour was double that in the forestomack contrary to this, colchamine (colcemide) accumulated in the course of the 24-hours 121.1% mitoses in the forestomack and 83.8% mitoses in the carcinoma. A greater number of mitoses in the tumour with the usual count is attributed to the fact that the mean 24-hour duration of mitosis of the remen carcinoma was 2.7 greater than in the epithelium of the forestomack.
前胃上皮细胞分裂的昼夜节律被证明与前胃可移植性（持续性）癌中的昼夜节律大体相似；这些组织中细胞分裂的持续时间在24小时内会发生变化。肿瘤中平均24小时有丝分裂活性是前胃的两倍。与此相反，秋水仙胺（秋水仙酰胺）在24小时内在前胃中积累了121.1%的有丝分裂，在癌中积累了83.8%的有丝分裂。肿瘤中通常计数的有丝分裂数量更多，这归因于瘤胃癌平均24小时有丝分裂持续时间比前胃上皮长2.7倍这一事实。
