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[Study of the effect of cAMP on the mitotic regimen in the esophageal epithelium of tumor-bearing mice].

作者信息

Volkov I N

出版信息

Biull Eksp Biol Med. 1977 Aug;84(8):215-7.

PMID:198044
Abstract

The mitotic activity and number of DNA-synthesizing cells in the epithelium of the esophagus of the tumour-bearing albino mice were studied for 24 hours after the injection of dibutyryl cyclic 3', 5'-AMP. It was shown that injection of the preparation led to the blocking of cells in the G2-phase of the mitotic cycle, and to prolongation of mitosis during the first hours of the experiment without changing the total number of cells undergoing mitosis in the course of 24 hours.

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