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慢性阻塞性肺疾病中肺动脉高压的放射学指标(作者译)

[Radiological indices of pulmonary hypertension in chronic obstructive pulmonary disease (author's transl)].

作者信息

Parent J G, Schrijen F, Viana R A

出版信息

Bull Eur Physiopathol Respir. 1976 Sep-Oct;12(5):637-50.

PMID:1016798
Abstract

This study attempted to correlate mean pulmonary arterial pressure with four radiological indices of pulmonary hypertension in 159 patients with chronic obstructive pulmonary disease. The mean pulmonary arterial pressure at rest (PAPR) and with exercise (PAPE) and four indices measured from the plain chest radiograph were considered. The measurements were: 1) DIP: the distance between the bifurcation of the right and left main pulmonary arteries, 2) DIP/T X 100 where T is a maximal thoracic diameter, 3) R: the diameter of the right descending pulmonary artery, and 4) R/h x 100 where h is T/2. The mean index values +/- SD obtained from three observers were: DIP = 11.4 +/- 1 cm, DIP/T x 100 = 36.1 +/- 3.5 R = 1.9 +/- 4cm, R/h x 100 = 12 +/- 2.7. An analysis of variation demonstrated that the interobserver error was unacceptable for R and R/h x 100 but small for DIP and DIP/T x 100. Increased PAP does not implicate high index values but high values specify abnormal PAP. The results suggest that DIP greater than 13 cm or DIP/T x 100 greater than 42 are diagnostic. A minority presented such values, but in 20 to 30% of these cases this preceded clinical or electrocardiographic manifestations of cor pulmonale.

摘要

本研究试图将159例慢性阻塞性肺疾病患者的平均肺动脉压与四个肺动脉高压的放射学指标相关联。研究考虑了静息时的平均肺动脉压(PAPR)、运动时的平均肺动脉压(PAPE)以及从胸部平片测量得到的四个指标。这些测量指标分别为:1)DIP:左右主肺动脉分叉处之间的距离;2)DIP/T×100,其中T为胸廓最大直径;3)R:右肺下动脉直径;4)R/h×100,其中h为T/2。由三名观察者得出的平均指标值±标准差为:DIP = 11.4±1厘米,DIP/T×100 = 36.1±3.5,R = 1.9±4厘米,R/h×100 = 12±2.7。方差分析表明,观察者间误差对于R和R/h×100来说不可接受,但对于DIP和DIP/T×100来说较小。肺动脉压升高并不意味着指标值高,但高指标值表明肺动脉压异常。结果表明,DIP大于13厘米或DIP/T×100大于42具有诊断意义。少数患者呈现出这样的值,但在这些病例中有20%至30%在肺心病的临床或心电图表现出现之前就已出现这些值。

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