Russo G E, Caramiello M S, Vitaliano E, De Marco C M, Pennacchia M, Giusti S, Vannini F, Mannini L, Avanzi G
Plasmapheresis and Dialysis Unit, Institute of 1 Clinical Medica, University of Rome, La Sanienza, Italy.
Transfus Sci. 1996 Dec;17(4):499-503.
Thirty-four patients affected by mixed cryoglobulinaemia have been submitted to treatment by apheresis (plasma exchange or double cascade filtration). The authors have monitored clinical, laboratory and, above all, haemorheological changes following therapy. The final results have shown mainly a reduction of plasma viscosity and consequently an improvement of the haemorheology of the affected organs. In conclusion, apheresis may be considered a successful therapy in patients with severe renal or neurological diseases due to mixed cryoglobulinaemia.
34例混合性冷球蛋白血症患者接受了血液分离术（血浆置换或双重级联过滤）治疗。作者监测了治疗后的临床、实验室变化，尤其是血液流变学变化。最终结果主要显示血浆粘度降低，从而改善了受累器官的血液流变学。总之，对于因混合性冷球蛋白血症导致的严重肾脏或神经系统疾病患者，血液分离术可被视为一种成功的治疗方法。
