Maliekal J, Bertch K E, Witte K W
Sonoma Valley Hospital, Sonoma, CA 95476.
Hosp Pharm. 1993 Oct;28(10):970-1, 975-7.
The advent of ready-to-use intravenous (IV) delivery systems, particularly small-volume parenterals less than 250 mL has contributed greatly to pharmacy and patient care. Since their introduction in the late 1970s, the availability and variety of systems have increased. The purpose of this article is to update practitioners on small-volume parenterals systems that have a large product availability requiring little manipulation to make the system patient-specific. Additional benefits such as extended stability, potential for decreasing waste of products, as well improved end-quality are also discussed. With the benefits described that these systems have over the traditional method of preparing small-volume parenterals, there is still hesitation to fully utilize these systems. The primary reason for this seems to be the issue of cost. With various rebate incentive programs offered by manufacturers as well as the benefits that the systems provide, ready-to-use IV delivery systems are comparable in price to the traditional method of preparing small-volume parenteral agents.
即用型静脉注射（IV）给药系统的出现，尤其是小于250毫升的小容量肠胃外给药制剂，极大地推动了药学和患者护理的发展。自20世纪70年代末引入以来，此类系统的可得性和种类都有所增加。本文旨在向从业者介绍小容量肠胃外给药系统的最新情况，这些系统有大量现成产品，只需进行少量操作就能使其针对特定患者。还讨论了其他益处，如延长稳定性、减少产品浪费的可能性以及提高最终质量。尽管这些系统相对于传统的小容量肠胃外给药制剂制备方法有上述诸多益处，但在充分利用这些系统方面仍存在犹豫。这样做的主要原因似乎是成本问题。随着制造商提供各种返利激励计划以及这些系统所带来的益处，即用型静脉注射给药系统的价格与传统的小容量肠胃外给药制剂制备方法相当。
