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接受术前冠状动脉血管成形术的患者进行非心脏大手术的心脏结局。

Cardiac outcome of major noncardiac surgery in patients undergoing preoperative coronary angioplasty.

作者信息

Jones S E, Raymond R E, Simpfendorfer C C, Whitlow P L

机构信息

Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195.

出版信息

J Invasive Cardiol. 1993 Jul-Aug;5(6):212-8.

Abstract

Patients with significant coronary artery disease are at increased risk for myocardial infarction and death when undergoing major noncardiac surgery, particularly vascular, thoracic and upper abdominal procedures. Revascularization with coronary bypass surgery has shown to be effective in reducing perioperative coronary events in such patients. Little data is available on the role of preoperative coronary angioplasty in this setting. The objective of this study was to determine the perioperative cardiac outcome in patients undergoing coronary angioplasty within six weeks of major noncardiac surgery. We analyzed our experience with 108 consecutive patients (85 males) with a mean age of 68 years (range 41-83) who underwent coronary angioplasty within 42 days of a major operative procedure, which was defined as either a vascular, thoracic or upper abdominal procedure. Multivessel disease was present in 48% of patients. Angioplasty success rate was 97% with 33 (31%) patients having more than one lesion dilated. Angioplasty complications included 1 stroke and 4 non-Q wave myocardial infarctions. The mean time from angioplasty to operative procedure was 14.5 days (range 0-41 days). Ninety six (91%) of the patients underwent vascular surgery--including 42 abdominal aneurysm repairs, 29 carotid endarterectomies, 21 lower extremity bypass operations and four renal artery bypass procedures. Eight patients had major abdominal surgery and one patient had a thoracic procedure. Postoperative cardiac complications included three non-Q wave myocardial infarctions and one Q-wave myocardial infarction which resulted in the only cardiac death (0.9%). There were no sustained ventricular arrhythmias.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

患有严重冠状动脉疾病的患者在接受非心脏大手术,尤其是血管、胸科和上腹部手术时,发生心肌梗死和死亡的风险会增加。冠状动脉搭桥手术进行血运重建已被证明可有效降低此类患者的围手术期冠状动脉事件。关于术前冠状动脉血管成形术在此种情况下的作用,目前可用的数据很少。本研究的目的是确定在非心脏大手术六周内接受冠状动脉血管成形术的患者的围手术期心脏结局。我们分析了108例连续患者(85例男性)的经验,这些患者平均年龄68岁(范围41 - 83岁),在大手术(定义为血管、胸科或上腹部手术)42天内接受了冠状动脉血管成形术。48%的患者存在多支血管病变。血管成形术成功率为97%,33例(31%)患者扩张了不止一处病变。血管成形术并发症包括1例中风和4例非Q波心肌梗死。从血管成形术到手术的平均时间为14.5天(范围0 - 41天)。96例(91%)患者接受了血管手术,包括42例腹主动脉瘤修复术、29例颈动脉内膜切除术、21例下肢搭桥手术和4例肾动脉搭桥手术。8例患者进行了上腹部大手术,1例患者进行了胸科手术。术后心脏并发症包括3例非Q波心肌梗死和1例Q波心肌梗死,后者导致了唯一的心脏死亡(0.9%)。没有持续性室性心律失常。(摘要截断于250字)

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