Allen J R, Helling T S, Hartzler G O
Department of Surgery, University of Missouri-Kansas City School of Medicine.
Surg Gynecol Obstet. 1991 Oct;173(4):285-8.
The benefit of coronary artery bypass grafting (CABG) in patients with coronary artery disease (CAD) who require extensive surgical procedures not involving the heart has been established. During the past decade, percutaneous transluminal coronary angioplasty (PTCA) has been developed as an alternative therapy to CABG for patients with CAD. In an attempt to determine the safety of other surgical procedures after PTCA, we retrospectively reviewed 148 patients who underwent 193 surgical procedures from four to 1,867 days after PTCA for CAD. Seventy-two patients had surgical treatment within 90 days of PTCA. Thirty-five patients had CABG prior to PTCA, and 113 had PTCA as the initial treatment for CAD. Four patients died postoperatively, only one death was cardiac in origin. One patient had a myocardial infarction postoperatively (the one cardiac death). Fifteen patients had other cardiac complications (nine patients with arrhythmias and six with myocardial ischemia). Patients operated upon within 90 days of PTCA had no increased cardiac morbidity, although the one myocardial infarction occurred in this group. No difference in cardiac morbidity occurred in patients with multivessel CAD treated by PTCA compared with single vessel disease. However, patients more than 60 years of age had more cardiac problems (16 of 110) than those less than 60 years of age (zero of 38) (p = 0.01). Treatment of CAD by PTCA protects the myocardium from fatal cardiac events and myocardial infarction during subsequent noncardiac operative procedures even early (less than 90 days) in the post-PTCA period. Older patients seem to be at higher risk, however, for nonfatal cardiac complications.
冠状动脉旁路移植术(CABG)对于患有冠状动脉疾病(CAD)且需要进行不涉及心脏的广泛外科手术的患者的益处已得到证实。在过去十年中,经皮腔内冠状动脉成形术(PTCA)已发展成为CAD患者CABG的替代疗法。为了确定PTCA后进行其他外科手术的安全性,我们回顾性分析了148例患者,这些患者在PTCA治疗CAD后的4至1867天内接受了193次外科手术。72例患者在PTCA后90天内接受了手术治疗。35例患者在PTCA之前接受了CABG,113例患者将PTCA作为CAD的初始治疗方法。4例患者术后死亡,仅1例死亡源于心脏原因。1例患者术后发生心肌梗死(即1例心脏死亡)。15例患者出现其他心脏并发症(9例心律失常,6例心肌缺血)。在PTCA后90天内接受手术的患者心脏发病率没有增加,尽管该组发生了1例心肌梗死。与单支血管疾病患者相比,PTCA治疗的多支血管CAD患者的心脏发病率没有差异。然而,年龄超过60岁的患者(110例中的16例)比年龄小于60岁的患者(38例中的0例)有更多的心脏问题(p = 0.01)。PTCA治疗CAD可使心肌在随后的非心脏手术过程中免受致命性心脏事件和心肌梗死的影响,即使在PTCA后的早期(少于90天)也是如此。然而,老年患者发生非致命性心脏并发症的风险似乎更高。