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持续质量改进可缩短住院时间并减少不良事件:一项介入心脏病学项目的案例研究

Continuous quality improvement decreases length of stay and adverse events: a case study in an interventional cardiology program.

作者信息

Hashimoto H, Bohmer R M, Harrell L C, Palacios I F

机构信息

Harvard School of Public Health, Boston, MA, USA.

出版信息

Am J Manag Care. 1997 Aug;3(8):1141-50.

Abstract

A study was performed to assess the effectiveness of continuous quality improvement in achieving a better quality of care for patients undergoing coronary interventions. Increasing utilization of new coronary interventional devices has incurred a higher incidence of complications, prolonged hospital stay, and related costs. Using a clinical information system, we adopted continuous quality improvement to control the incidence of complications and postprocedural length of stay. Multiple regression analysis and a matched case-control study were performed to detect complications related to postprocedural length of stay and their causes among 342 patients. The results led to the modification of the postprocedural heparin anticoagulation protocol, which was followed by the introduction of a ticlopidine-based poststent anticoagulation regimen. Two sequential groups of patients (n = 261, n = 266) were selected to compare postprocedural length of stay and frequency of complications with those for the first group. Adjustments were made for patients and procedural characteristics through stratification and multiple regression methods. Blood transfusion was the most important predictor of prolonged hospital stay (partial R2 = 0.26, P < 0.01). A high level of postprocedural anticoagulation and intracoronary stent use were significantly associated with blood transfusion (P = 0.01, P = 0.02, respectively). The comparison among the three groups showed that heparin protocol change reduced only postprocedural length of stay (P < 0.001) for patients without stents, whereas the stent change in anticoagulation protocol significantly reduced both transfusion and hospital stay for patients with stents (P < 0.001, P < 0.05, respectively). Continuous quality improvement based on clinical information is promising to control both complications and hospital costs. Physician involvement is necessary throughout the process.

摘要

开展了一项研究,以评估持续质量改进在为接受冠状动脉介入治疗的患者实现更高护理质量方面的有效性。新型冠状动脉介入装置使用的增加导致并发症发生率更高、住院时间延长以及相关费用增加。我们利用临床信息系统采用持续质量改进来控制并发症发生率和术后住院时间。对342例患者进行了多元回归分析和匹配病例对照研究,以检测与术后住院时间相关的并发症及其原因。结果促使对术后肝素抗凝方案进行了修改,随后引入了基于噻氯匹定的支架置入后抗凝方案。选择两组连续的患者(n = 261,n = 266),将其术后住院时间和并发症发生率与第一组患者进行比较。通过分层和多元回归方法对患者和手术特征进行了调整。输血是住院时间延长的最重要预测因素(偏R2 = 0.26,P < 0.01)。术后高抗凝水平和冠状动脉内支架使用与输血显著相关(分别为P = 0.01,P = 0.02)。三组之间的比较表明,肝素方案的改变仅降低了无支架患者的术后住院时间(P < 0.001),而支架抗凝方案的改变显著降低了有支架患者的输血率和住院时间(分别为P < 0.001,P < 0.05)。基于临床信息的持续质量改进有望控制并发症和医院成本。在整个过程中医生的参与是必要的。

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