利用离体灌注肺研究内源性和外源性化学物质的摄取、代谢及释放。
Studies on the uptake, metabolism, and release of endogenous and exogenous chemicals by use of the isolated perfused lung.
作者信息
Anderson M W, Eling T E
出版信息
Environ Health Perspect. 1976 Aug;16:77-81. doi: 10.1289/ehp.761677.
Abstract
The isolated perfused lung is a valuable tool for studying many lung functions. The kinds of information one can obtain from the isolated perfused lung are illustrated by examples from our studies on the uptake, accumulation, and metabolism of endogenous and exogenous chemicals.
摘要
离体灌注肺是研究多种肺功能的重要工具。我们对内源性和外源性化学物质的摄取、蓄积及代谢的研究实例，说明了可从离体灌注肺获得的信息类型。
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Studies on the uptake, metabolism, and release of endogenous and exogenous chemicals by use of the isolated perfused lung.利用离体灌注肺研究内源性和外源性化学物质的摄取、代谢及释放。
Environ Health Perspect. 1976 Aug;16:77-81. doi: 10.1289/ehp.761677.
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Metabolism of xenobiotics by the isolated perfused lung. Comparison with in vitro incubations.离体灌注肺对外源化学物的代谢。与体外孵育的比较。
Drug Metab Dispos. 1974 Sep-Oct;2(5):433-42.
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Accumulation of amines in the isolated perfused rabbit lung.
J Pharmacol Exp Ther. 1974 May;189(2):456-66.
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Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs.
J Pharmacol Exp Ther. 1973 Sep;186(3):482-97.
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