秀丽隐杆线虫中的生物胺。
Biogenic amines in the Caenorhabditis briggsae.
作者信息
Kisiel M J, Deubert K H, Zuckerman B M
出版信息
Exp Aging Res. 1976 Jan;2(1):37-44. doi: 10.1080/03610737608257975.
PMID:1017438
Abstract
Dopamine, epinephrine, norepinephrine and serotonin were demonstrated from homogenates of Caenrohabditis briggsae by two-dimensional thin layer chromotography and the identification confirmed by gas liquid chromtography. In Vitro studies with 14C precursors of these biogenic amines demonstrate the ability of C. briggsae to synthesize each compound. The results provide required preliminary data for studying the neurophysiology of aging utilizing the nematode as a model.
摘要
通过二维薄层色谱法从秀丽隐杆线虫匀浆中检测到多巴胺、肾上腺素、去甲肾上腺素和血清素，并通过气相色谱法进行了鉴定确认。使用这些生物胺的14C前体进行的体外研究表明，秀丽隐杆线虫具有合成每种化合物的能力。这些结果为利用线虫作为模型研究衰老的神经生理学提供了所需的初步数据。
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