Kaliman P A, Sergienko N G, Luchko N A, Brovina N N
Vopr Med Khim. 1983 Mar-Apr;29(2):69-73.
Content of tryptophane, tyrosine, serotonin, noradrenaline, adrenaline and dopamine was studied in blood serum and various brain regions of rats with genetically determined spontaneous form of hypertension. The arterial pressure of these animals was shown to depend on activity of noradrenaline-, serotonin- and dopaminergic systems of brain. Oppositely directed alterations in content of dopamine and noradrenaline were observed in various brain regions apparently as a result of changes in activity of the enzymes involved in the amines synthesis and degradation.
对具有遗传性自发性高血压的大鼠血清及不同脑区中的色氨酸、酪氨酸、血清素、去甲肾上腺素、肾上腺素和多巴胺含量进行了研究。结果表明，这些动物的动脉血压取决于脑内去甲肾上腺素能、血清素能和多巴胺能系统的活性。在不同脑区观察到多巴胺和去甲肾上腺素含量呈相反方向的变化，这显然是由于参与胺类合成和降解的酶活性发生改变所致。
