Takigawa M, Aoshima T
Dermatologica. 1976;153(3):202-6. doi: 10.1159/000251118.
A Japanese girl aged 15 months had an eruption of 3 months' duration on the face, trunk, and extremities except for the palms and soles. The lesions were infiltrated papules varying from 2 to 3 mm in diameter. Blood eosinophilia of 5% was demonstrated. Skin biopsy specimen revealed a necrobiotic palisading granuloma in the corium. All lesions began to subside after 1 weeks' administration of oral corticosteroid and completely involuted in 2 months. A possible etiologic role of insect bites was considered.
一名15个月大的日本女孩，其面部、躯干及四肢（手掌和脚底除外）出现皮疹，病程3个月。皮损为直径2至3毫米的浸润性丘疹。血液嗜酸性粒细胞增多达5%。皮肤活检标本显示真皮层有栅栏状坏死性肉芽肿。口服皮质类固醇治疗1周后，所有皮损开始消退，2个月内完全消退。考虑昆虫叮咬可能具有病因学作用。
