A case of granuloma multiforme is reported. Granuloma multiforme has been seen so far only in blacks from Nigeria or East Africa. The disease does not affect children and adolescents. Common sites of infection are arms, chest, back, neck, and head. The differential diagnosis is tuberculoid leprosy and granuloma anulare. Granuloma multiforme also shows similarity to that of granuloma anulare or, if more of a tuberculoid nature, to that of sarcoidosis or that of granulomatosis disciformis chronica et progressiva Miescher. The etiology of granuloma multiforme is unknown. It may respond to intralesional corticosteroid therapy or show involution following a diagnostic biopsy. In the reported case response to intralesional corticosteroid suspension and topical application of dimethyldiphenylendisulfide was very satisfactory.
报告了一例多形性肉芽肿病例。迄今为止，多形性肉芽肿仅在来自尼日利亚或东非的黑人中被发现。该疾病不影响儿童和青少年。常见感染部位为手臂、胸部、背部、颈部和头部。鉴别诊断为结核样麻风病和环状肉芽肿。多形性肉芽肿也与环状肉芽肿相似，或者如果更具结核样性质，则与结节病或慢性进行性盘状肉芽肿（米舍尔病）相似。多形性肉芽肿的病因尚不清楚。它可能对皮损内注射皮质类固醇治疗有反应，或在诊断性活检后自行消退。在所报告的病例中，对皮损内注射皮质类固醇混悬液和局部应用二甲基二苯二硫化物的反应非常令人满意。
