Snape W J
Am J Manag Care. 1997 May;3(5):766-71.
Heartburn, the major symptom of gastrointestinal reflux disease (GERD), is a common condition that is usually self-treated with over-the-counter products. For patients with severe or recurrent symptoms of GERD, pharmacologic therapy includes acid suppression with H2-receptor antagonists and proton pump inhibitors, and, alternatively, the use of prokinetic agents. While all of these are efficacious, given its high efficacy in nonerosive and mild-to-moderate erosive esophagitis, the prokinetic agent cisapride deserves significant consideration in this patient population.
烧心是胃食管反流病（GERD）的主要症状，是一种常见病症，通常使用非处方产品自行治疗。对于GERD症状严重或反复出现的患者，药物治疗包括使用H2受体拮抗剂和质子泵抑制剂抑制胃酸，或者使用促动力药。虽然所有这些药物都有效，但鉴于促动力药西沙必利在非糜烂性和轻度至中度糜烂性食管炎中疗效显著，在这类患者群体中值得重点考虑。
