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紧张型和非紧张型精神病患者的血清铁

Serum iron in catatonic and noncatatonic psychotic patients.

作者信息

Peralta V, Cuesta M J, Mata I, Serrano J F, Perez-Nievas F, Natividad M C

机构信息

Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain.

出版信息

Biol Psychiatry. 1999 Mar 15;45(6):788-90. doi: 10.1016/s0006-3223(98)00137-1.

DOI:10.1016/s0006-3223(98)00137-1
PMID:10188010
Abstract

BACKGROUND

Since low serum iron has been reported in a variety of neuropsychiatric motor disorders, this study was conducted to examine serum iron in patients with a catatonic disorder.

METHODS

Forty catatonic and 40 noncatatonic psychotic patients were studied in relation to serum iron levels. The association of serum iron with other clinical variables was also examined.

RESULTS

Catatonics had significantly lower mean serum iron than noncatatonics. Ferropenia (serum iron < 50 micrograms/dL) was significantly more prevalent in the catatonic (35%) than in the noncatatonic (7.5%) group. Severity of catatonic symptoms was inversely correlated with level of serum iron, this being due to the negative catatonic symptoms (r = -.34, p = .002).

CONCLUSIONS

A subgroup of catatonic patients had ferropenia. Lower serum iron level was associated with both the presence of a categorically defined catatonic syndrome and the severity of the negative catatonic symptoms.

摘要

背景

由于在多种神经精神性运动障碍中均有低血清铁的报道,因此开展本研究以检测紧张症患者的血清铁。

方法

对40例紧张症患者和40例非紧张症精神病患者的血清铁水平进行了研究。还检测了血清铁与其他临床变量之间的关联。

结果

紧张症患者的平均血清铁显著低于非紧张症患者。缺铁性贫血(血清铁<50微克/分升)在紧张症患者组(35%)中比在非紧张症患者组(7.5%)中更为普遍。紧张症症状的严重程度与血清铁水平呈负相关,这是由于阴性紧张症症状所致(r = -.34,p = .002)。

结论

一部分紧张症患者存在缺铁性贫血。较低的血清铁水平与明确界定的紧张症综合征的存在以及阴性紧张症症状的严重程度均相关。

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