Leyenaar J, Sutherland H J, Lockwood G A, Martin L J, Kriukov V, Greenberg C V, Boyd N F
Division of Epidemiology and Statistics, Ontario Cancer Institute, Toronto, Canada.
Cancer Causes Control. 1998 Dec;9(6):601-10. doi: 10.1023/a:1008827428524.
While decreased intake of dietary fat may have significant positive effects on women's health by reducing the risk of cancer and other diseases, little research has been carried out to determine the potential adverse effects of dietary fat reduction. This study compares the self-reported physical and emotional health of 402 low fat intervention and control group participants in the Canadian Diet and Breast Cancer Prevention Trial.
Subjects who had been participating in the dietary intervention trial for at least 2 years completed 3 mailed questionnaires: two designed to assess physical and emotional health (MOS 36-Item Short-Form Health Survey (SF-36) and the Women's Health Questionnaire (WHQ)) and a Health Practices Survey.
There were no significant differences between the study groups on total scores or any of the subscales/health domains for the SF-36 or the WHQ. In premenopausal women only, intervention group subjects scored significantly lower on the vasomotor symptoms scale, indicating less symptom experience. Frequency of visits to physicians and alternative health practitioners were not significantly different between the study groups.
The results of this study suggest that participation in a low-fat, high-carbohydrate dietary intervention did not have any detrimental effects on participants' self-reported physical health or emotional well-being.
虽然减少膳食脂肪摄入可能通过降低癌症和其他疾病的风险对女性健康产生显著的积极影响，但很少有研究来确定减少膳食脂肪摄入的潜在不良影响。本研究比较了加拿大饮食与乳腺癌预防试验中402名低脂干预组和对照组参与者自我报告的身体和情绪健康状况。
参与饮食干预试验至少2年的受试者完成了3份邮寄问卷：两份旨在评估身体和情绪健康状况（医学结局研究36项简短健康调查（SF - 36）和女性健康问卷（WHQ））以及一份健康行为调查。
在SF - 36或WHQ的总分或任何子量表/健康领域方面，研究组之间没有显著差异。仅在绝经前女性中，干预组受试者在血管舒缩症状量表上的得分显著较低，表明症状体验较少。研究组之间看医生和看替代疗法从业者的频率没有显著差异。
本研究结果表明，参与低脂、高碳水化合物饮食干预对参与者自我报告的身体健康或情绪幸福感没有任何不利影响。
