Cloonan J M, Donald T G, Neale C, Wilcken D E
Pathology. 1976 Oct;8(4):313-20. doi: 10.3109/00313027609101494.
An indirect haemaglutination method was developed for the immunochemical detection of myoglobin in human urine. Myoglobin was found in the urine of 84% of 44 patients with acute myocardial infarction. In contrast, it was detected in the urine of 2.7% of 147 control subjects and in none of a control group of 15 patients who had received intramuscular injections. In patients with myocardial infarction, myoglobin was detected in most but not all urine specimens collected between 10 and 50 hours after the onset of chest pain. The results suggest that the detection of myoglobin in urine may be a valuable addition to present tests for the diagnosis of acute myocardial infarction.
已开发出一种间接血凝方法用于免疫化学检测人尿中的肌红蛋白。在44例急性心肌梗死患者中，84%的患者尿液中发现了肌红蛋白。相比之下，在147名对照受试者中，2.7%的受试者尿液中检测到了肌红蛋白，而在15名接受肌肉注射的对照组患者中均未检测到。在心肌梗死患者中，胸痛发作后10至50小时采集的大多数但并非所有尿液样本中都检测到了肌红蛋白。结果表明，尿液中肌红蛋白的检测可能是目前急性心肌梗死诊断检测的一项有价值的补充。
