Paut O, André N, Fabre P, Sobraquès P, Drouet G, Arditti J, Camboulives J
Département d'anesthésie-réanimation pédiatrique, Salvator hospital, Marseille, France.
Paediatr Anaesth. 1999;9(2):171-4. doi: 10.1046/j.1460-9592.1999.9220325.x.
We describe a five-week-old boy who had seizures and extreme hypernatraemia secondary to ingesting an improper home-made formula. Initial sodium concentration was 211 mmol.l-1. Other clinical and biological features were moderate dehydration and renal insufficiency with generous urine output and high urinary sodium concentration. Fluid therapy with hypotonic dextrose solution corrected the volume deficit in 48 h and progressively decreased the serum sodium concentration. During ICU stay the patient developed recurrent episodes of seizures and pulmonary oedema requiring mechanical ventilation for five days. Recovery was complete with no abnormal sequelae after a ten-month follow-up. Salt poisoning is in unusual cause of extreme hypernatraemia. It can be safely managed with fluid therapy alone if urine output is preserved, with progressive decrease of serum sodium as target. If this condition is recognized, outcome should be favourable.
我们描述了一名5周大的男婴,他因摄入不当的自制配方奶而出现癫痫发作和极度高钠血症。初始钠浓度为211 mmol·l-1。其他临床和生物学特征为中度脱水和肾功能不全,尿量丰富且尿钠浓度高。用低渗葡萄糖溶液进行液体疗法在48小时内纠正了容量不足,并逐渐降低了血清钠浓度。在重症监护病房住院期间,患者出现反复发作的癫痫和肺水肿,需要机械通气5天。经过10个月的随访,患者完全康复,没有异常后遗症。盐中毒是极度高钠血症的不常见原因。如果尿量得以维持,仅通过液体疗法即可安全处理,目标是使血清钠逐渐降低。如果能认识到这种情况,预后应该良好。