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在孟加拉国一家城市腹泻病医院,仅使用口服补液盐溶液成功治疗了一名血清钠为201毫摩尔/升的幼儿。

Use of only oral rehydration salt solution for successful management of a young infant with serum sodium of 201 mmol/L in an urban diarrhoeal diseases hospital, Bangladesh.

作者信息

Chisti Mohammod J, Pietroni Mark A C, Alom Mohammad Samsul, Smith Jonathan Harvey

机构信息

icddr,b, GPO Box 128, Dhaka 1000, Bangladesh.

出版信息

J Health Popul Nutr. 2012 Sep;30(3):371-6. doi: 10.3329/jhpn.v30i3.12301.

Abstract

A boy aged 4 months 7 days was admitted to the Intensive Care Unit (ICU) of the Dhaka Hospital of icddr,b, Dhaka, Bangladesh, with the problems of acute watery diarrhoea with some dehydration, pneumonia, lethargy, and hypernatraemia (serum sodium of 201 mmol/L). Correction for hypernatraemia was tried by using only oral rehydration salt (ORS) solution. Seizures occurred during correction of the hypernatraemia. These were difficult to control and required three doses of injection lorazepam, a loading dose of injection phenobarbitone, followed by injection phenytoin and finally two doses of injection mannitol (even though there was no clinical or imaging evidence by ultrasonography or computed tomography of cerebral oedema). The correction was continued with ORS, and all the anticonvulsants were successfully weaned without any further seizures, and the patient recovered without any overt neurological sequelae. We present a case report of extreme hypernatraemia, which was successfully managed using only ORS.

摘要

一名4个月7天大的男童因急性水样腹泻伴轻度脱水、肺炎、嗜睡和高钠血症(血清钠201 mmol/L)入住孟加拉国达卡icddr,b达卡医院重症监护病房(ICU)。仅使用口服补液盐(ORS)溶液尝试纠正高钠血症。在纠正高钠血症过程中发生了惊厥。惊厥难以控制,需要注射三剂劳拉西泮、一剂负荷量苯巴比妥注射液,随后注射苯妥英,最后注射两剂甘露醇(尽管超声或计算机断层扫描均无脑水肿的临床或影像学证据)。继续用ORS进行纠正,所有抗惊厥药物均成功撤停,未再发生惊厥,患者康复,无明显神经后遗症。我们报告一例极重度高钠血症病例,仅用ORS成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8424/3489953/af17d69f8c4c/jhpn0030-0371_f01.jpg

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