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起源于脑桥的髓母细胞瘤

[Medulloblastoma originating in the pons].

作者信息

Nagai M, Nakayama S, Kusunoki H, Sasaki M, Yamada R

机构信息

Department of Surgical Neurology, Ibaraki Prefectural Central Hospital, Japan.

出版信息

No Shinkei Geka. 1999 Mar;27(3):281-5.

Abstract

Medulloblastoma usually originates in the cerebellum. We report here a case of medulloblastoma originating in the pons. Pontine medulloblastoma is extremely rare, with only one report in the literature. An 11-year-old girl was admitted to our hospital with vertigo. Magnetic resonance imaging (MRI) revealed a tumor originating in the pons. On the 4th day after admission, the tumor bled. Because the patient's life was in danger from brain herniation, hematoma removal and tumor resection were carried out. The diagnosis was medulloblastoma. After surgery, the patient received radiation therapy and chemotherapy. Unlike tumors originating in the cerebellum, this tumor did not seem to be effectively reduced by these therapies. Radiation therapy and chemotherapy may not be effective for medulloblastoma originating in the pons. We considered it necessary to make a histological diagnosis even though the tumor originated in the pons and resection was difficult technically.

摘要

髓母细胞瘤通常起源于小脑。我们在此报告一例起源于脑桥的髓母细胞瘤。脑桥髓母细胞瘤极为罕见,文献中仅有一例报道。一名11岁女孩因眩晕入院。磁共振成像(MRI)显示脑桥有一个肿瘤。入院后第4天,肿瘤出血。由于患者因脑疝生命垂危,遂进行了血肿清除和肿瘤切除。诊断为髓母细胞瘤。术后,患者接受了放疗和化疗。与起源于小脑的肿瘤不同,这些治疗方法似乎未能有效缩小该肿瘤。放疗和化疗可能对起源于脑桥的髓母细胞瘤无效。尽管肿瘤起源于脑桥且技术上难以切除,我们认为进行组织学诊断是必要的。

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