Minev B R, Chavez F L, Mitchell M S
Center for Biological Therapy and Melanoma Research, Cancer Center, University of California-San Diego, La Jolla 92093-0061, USA.
Pharmacol Ther. 1999 Feb;81(2):121-39. doi: 10.1016/s0163-7258(98)00039-4.
Cancer vaccines are a promising tool in the hands of the clinical oncologist. We have summarized the most recent findings and achievements in this exciting field. Tumor-associated antigens, as a basis for the new cancer vaccines, are reviewed. We emphasize novel approaches for the design of safe and more effective vaccines for cancer. We also discuss the possible clinical applications and the future prospects for vaccine development.
癌症疫苗是临床肿瘤学家手中一项很有前景的工具。我们总结了这个令人兴奋的领域的最新发现和成果。作为新型癌症疫苗基础的肿瘤相关抗原也在文中进行了综述。我们着重介绍了设计安全且更有效的癌症疫苗的新方法。我们还讨论了疫苗开发可能的临床应用和未来前景。
