Kaplan Johanne M
Genzyme Corporation, Framingham, Massachusetts 01701-9322, USA.
Drugs Today (Barc). 2004 Nov;40(11):913-29. doi: 10.1358/dot.2004.40.11.872580.
The use of tumor vaccines as a therapeutic modality for the treatment of cancer is a very exciting and promising area of research. Unlike chemotherapy, vaccination against tumor antigens has the potential to specifically target cancer cells without damage to normal tissues or debilitating side effects. Recent progress in immunology and tumor biology has allowed for the development of new vaccination strategies and approaches to enhance clinical efficacy.
将肿瘤疫苗用作治疗癌症的一种治疗方式是一个非常令人兴奋且前景广阔的研究领域。与化疗不同,针对肿瘤抗原进行疫苗接种有潜力特异性地靶向癌细胞,而不会损害正常组织或产生使人虚弱的副作用。免疫学和肿瘤生物学的最新进展使得开发新的疫苗接种策略和方法以提高临床疗效成为可能。