Siegel H S, Latimer J W, Drury L N, Loy E W
Poult Sci. 1976 Nov;55(6):2319-26. doi: 10.3382/ps.0552319.
White rock chicks were fed a commercial crumbles ration with approximately 1.0 p.p.m. of the active ingreient of technical grade dieldrin added to it. The treated feed was replaced by uncontaminated feed at various times from two to eight weeks of age. Equations were computed to describe the accumulation and depletion of the insecticide in visceral adipose tissue. Accumulations in females were described by polynomial equations with significant quadratic coefficients which indicated that the rate of accumulation leveled off between six and eight weeks. Accumulation rates in males were essentially linear through ten weeks. After removal of dieldrin from the feed, insecticide depletion from fat could be described in both sexes by equations for power curves. Replacement of contaminated feed with uncontaminated feed by two or three weeks of age resulted in concentrations at control or background levels by eight weeks of age. Replacement of contaminated feed with non-contaminated feed at ages later than three weeks did not bring concentrations below those acceptable as non-hazardous for human consumption.
给白色来亨鸡雏鸡喂食一种商业颗粒饲料,其中添加了约百万分之一(1.0 ppm)技术级狄氏剂的活性成分。在雏鸡2至8周龄的不同时间,用未受污染的饲料替换经处理的饲料。计算了描述杀虫剂在内脏脂肪组织中积累和消耗的方程式。雌性体内的积累情况用具有显著二次系数的多项式方程描述,这表明积累速率在6至8周之间趋于平稳。雄性体内的积累速率在10周内基本呈线性。从饲料中去除狄氏剂后,两性脂肪中杀虫剂的消耗可用幂曲线方程描述。在2或3周龄时用未受污染的饲料替换受污染的饲料,到8周龄时浓度达到对照或背景水平。在3周龄以后用未受污染的饲料替换受污染的饲料,并没有使浓度降至对人类消费而言可接受的无危害水平以下。