Gallego-Iniesta M, Pertierra-Rimada E, Gálvez M
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;86(2):289-94. doi: 10.1016/0742-8413(87)90081-8.
The quantity of dieldrin accumulated in liver, kidney, heart, gizzard, lung, muscle, and intestine with contents, of broiler chickens fed with feed contaminated by this insecticide, was determined by gas chromatography analysis. The doses used were 60, 90, 120, 200 and 240 ppm. The influence of the doses used in the quantity of dieldrin accumulated in the different organs, the relationship between the doses administered, organs and quantity accumulated, and the toxicological consequences of the contamination were studied. The results show that the doses used did not significantly affect the quantity of dieldrin accumulated by the different organs. The relationship doses-organ-quantity accumulated shows that the muscle accumulates equal dieldrin at all the doses used. The differences in the dieldrin accumulated at different doses increases with the metabolic function of the organs. The principal symptoms of intoxication were anorexia, convulsions and tremors, which indicated that the nervous system is a major site of activity.
通过气相色谱分析，测定了用受这种杀虫剂污染的饲料喂养的肉鸡肝脏、肾脏、心脏、砂囊、肺、肌肉和肠道中积累的狄氏剂含量。使用的剂量分别为60、90、120、200和240 ppm。研究了所用剂量对不同器官中狄氏剂积累量的影响、给药剂量、器官与积累量之间的关系以及污染的毒理学后果。结果表明，所用剂量对不同器官中狄氏剂的积累量没有显著影响。剂量-器官-积累量的关系表明，在所有使用的剂量下，肌肉积累的狄氏剂量相等。不同剂量下积累的狄氏剂差异随着器官的代谢功能而增加。中毒的主要症状是厌食、惊厥和震颤，这表明神经系统是主要的作用部位。
