Traxer O, Lottmann H, Archambaud F, Helal B, Mercier Pageyral B
Service de Chirurgie Urologique Pédiatrique, Fondation Hôpital Saint-Joseph, Paris, France.
Prog Urol. 1998 Sep;8(4):502-6.
This study evaluated the long-term effects of extra-corporeal shock-wave lithotripsy (ESWL) on the renal parenchyma of children using DMSA-Tc 99m scintigraphy.
Between November 1989 and April 1997, twenty-three children wee treated for renal stones using a SONOLITH 3000 lithotriptor (Technomed-Corp. Evaluation of treatment and its consequences was based on clinical examination, conventional imaging and comparison with DMSA-TC 99m renal scintigraphy performed the day before and at least 6 months after treatment.
The success rate (fragmented and eliminated stones) was 90% at 6 months. Long-term follow-up did not reveal any alteration of blood pressure or renal function. Scintigraphic examinations did not demonstrate any significant parenchymal lesions attributable to treatment.
Extracorporeal shock wave lithotripsy is effective in adults and young children. Its safety on the renal parenchyma was demonstrated during this study. However, evaluation of larger series with the use of other lithotriptors is necessary before reaching any definitive conclusions.
本研究采用锝-99m二巯丁二酸（DMSA-Tc 99m）肾闪烁扫描评估体外冲击波碎石术（ESWL）对儿童肾实质的长期影响。
1989年11月至1997年4月期间，23名儿童使用SONOLITH 3000碎石机（Technomed公司）治疗肾结石。治疗及其后果的评估基于临床检查、传统影像学检查，并与治疗前及治疗后至少6个月进行的DMSA-Tc 99m肾闪烁扫描结果进行比较。
6个月时成功率（结石破碎并排出）为90%。长期随访未发现血压或肾功能有任何改变。闪烁扫描检查未显示任何因治疗导致的明显实质病变。
体外冲击波碎石术对成人和儿童均有效。本研究证实了其对肾实质的安全性。然而，在得出任何明确结论之前，有必要使用其他碎石机对更多病例进行评估。
