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[葡萄牙人群样本中幽门螺杆菌对大环内酯类和咪唑类药物的耐药性概况]

[Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population].

作者信息

Rosário M, Caetano J M, Pessanha M A, Marote G, da Silva J A, Caetano J A

机构信息

Serviço de Gastroenterologia, Instituto Clinico e Imunológico de Lisboa.

出版信息

Acta Med Port. 1998 Dec;11(12):1069-72.

PMID:10192979
Abstract

We studied the sensitivity of H. pylori to clarithromycin and metronidazole, as well as the sensitivity and specificity of H. pylori culture, urease test and histology on a sample of 166 Portuguese patients. We observed a prevalence of 5.8% resistance to clarithromycin and 60% resistance to metronidazole. The sensitivity and specificity for the diagnostic tests were: culture 98% and 100%, urease test 98% and 91%, histology 50% and 95%, respectively.

摘要

我们对166名葡萄牙患者的样本研究了幽门螺杆菌对克拉霉素和甲硝唑的敏感性,以及幽门螺杆菌培养、尿素酶试验和组织学检查的敏感性和特异性。我们观察到对克拉霉素的耐药率为5.8%,对甲硝唑的耐药率为60%。诊断测试的敏感性和特异性分别为:培养98%和100%,尿素酶试验98%和91%,组织学检查50%和95%。

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