一名急性重症哮喘患者对羟乙基淀粉（200/0.5）发生中度严重类过敏反应。

Moderately severe anaphylactoid reaction to pentastarch (200/0.5) in a patient with acute severe asthma.

作者信息

Kannan S, Milligan K R

机构信息

Intensive Care Unit, Belfast City Hospital, Belfast, UK.

出版信息

Intensive Care Med. 1999 Feb;25(2):220-2. doi: 10.1007/s001340050820.

DOI:10.1007/s001340050820

PMID:10193552

Abstract

The use of synthetic colloids for resuscitation and volume replacement is common in the intensive care unit. Although adverse reactions have been reported to colloid solutions, the incidence of severe reactions to the starch derivatives is low. We report a case of an anaphylactoid reaction to pentastarch (200/0.5) in a young asthmatic who received it as a fluid challenge in the intensive care unit. The pathogenesis and implications of such a reaction in an asthmatic are discussed.

摘要

在重症监护病房，使用合成胶体进行复苏和容量替代很常见。尽管已有关于胶体溶液不良反应的报道，但对淀粉衍生物发生严重反应的发生率较低。我们报告了一例年轻哮喘患者在重症监护病房接受羟乙基淀粉（200/0.5）液体激发试验后发生类过敏反应的病例。并讨论了这种反应在哮喘患者中的发病机制及意义。