Ring J, Messmer K
Lancet. 1977 Feb 26;1(8009):466-9. doi: 10.1016/s0140-6736(77)91953-5.
All available colloid volume substitutes carry the risk of anaphylactoid reactions. In a multicentre prospective trial, 69 cases of anaphylactoid reactions have been observed among 200 906 infusions of colloid volume substitutes. The frequency of severe reactions (shock, cardiac and/or respiratory arrest) was 0-003% for plasma-protein solutions, 0-006% for hydroxyethyl starch, 0-008% for dextran, and 0-038% for gelatin solutions.
所有可用的胶体容量替代品都有类过敏反应的风险。在一项多中心前瞻性试验中,在200906次胶体容量替代品输注中观察到69例类过敏反应。血浆蛋白溶液严重反应(休克、心脏和/或呼吸骤停)的发生率为0.003%,羟乙基淀粉为0.006%,右旋糖酐为0.008%,明胶溶液为0.038%。