Ortqvist A, Hedlund J, Kalin M
Infektionskliniken, Karolinska sjukhuset, Stockholm.
Lakartidningen. 1999 Mar 17;96(11):1305-8.
Invasive pneumococcal diseases are associated with substantial mortality in the elderly. The incidence of such diseases, particularly that of bacteraemic pneumococcal pneumonia, has increased in Sweden during the past decade. At the same time, there is a growing problem with beta-lactam-resistant and multiresistant pneumococci in many nearlying countries. Although pneumococcal vaccine probably provides only limited protection against pneumococcal pneumonia in the elderly, it yields approximately 70 per cent protection against invasive pneumococcal disease. Pneumococcal vaccination should therefore be recommended to all those 65 years old and above, and a nationwide strategy developed to implement good coverage in the age group.
侵袭性肺炎球菌疾病与老年人的高死亡率相关。在过去十年中,此类疾病的发病率,尤其是血行性肺炎球菌肺炎的发病率在瑞典有所上升。与此同时,许多邻国对β-内酰胺耐药和多重耐药肺炎球菌的问题日益严重。尽管肺炎球菌疫苗可能仅为老年人提供有限的肺炎球菌肺炎防护,但它对侵袭性肺炎球菌疾病可提供约70%的防护。因此,应建议所有65岁及以上的老人接种肺炎球菌疫苗,并制定一项全国性战略以实现该年龄组的高接种覆盖率。