Ann Intern Med. 1982 Feb;96(2):206-7.
Vaccination with the now-available pneumococcal vaccine is recommended for persons with diseases and other conditions predisposing to the development of bacteremic pneumococcal pneumonia or increased risk of death from such infection. The value of vaccination on the basis of advanced age is not clear at this time. The vaccine will not eliminate all risk of pneumococcal pneumonia and patients with some immune deficiency states may not respond adequately to te vaccine. Revaccination should not be done at intervals of less than five years. More data are needed from adequately designed and executed studies of benefit from the vaccine in healthy elderly persons and high-risk populations. Physicians should pay particular attention ot specific diagnostic needs in pneumococcal infection.
对于患有易引发菌血症性肺炎球菌肺炎疾病或其他状况,以及此类感染导致死亡风险增加的人群,建议接种现有的肺炎球菌疫苗。目前,基于高龄进行接种的价值尚不明确。该疫苗无法消除所有肺炎球菌肺炎的风险,一些免疫缺陷状态的患者可能对疫苗反应不佳。再次接种的间隔时间不应少于五年。需要通过设计合理且执行良好的研究,获取更多关于该疫苗对健康老年人和高危人群益处的数据。医生应特别关注肺炎球菌感染的具体诊断需求。