Keller C, Brimacombe J, Rädler C, Pühringer F
Department of Anaesthesia and Intensive Care Medicine, Leopold-Franzens University, Innsbruck, Austria.
Anesth Analg. 1999 Apr;88(4):904-7. doi: 10.1097/00000539-199904000-00040.
In this randomized, controlled cadaver study, we tested the hypothesis that the standard laryngeal mask airway (LMA) and flexible laryngeal mask airway (FLMA) attenuate liquid flow between the esophagus and pharynx. Fifty fresh cadavers were studied in four LMA groups. Ten female cadavers had a size 4 LMA and 10 had a size 4 FLMA; 10 male cadavers had a size 5 LMA and 10 had a size 5 FLMA; 5 male and 5 female cadavers functioned as controls. The chest was opened, and the infusion set of a pressure-controlled, continuous flow pump was inserted into the esophagus and ligated into place. Esophageal pressure was increased in 2-cm H2O increments. Regurgitation pressure was the esophageal pressure at which fluid was first seen with a fiberoptic scope in the hypopharynx (control group) and above the cuff or within the bowl (LMA groups). This was performed in the LMA groups at 0-40 mL cuff volume in 10-mL increments. Mean (95% confidence interval) regurgitation pressure for the control group was 7 (6-8) cm H2O and for the LMA groups combined was 19 (17-20) cm H2O at 0 mL cuff volume, 47 (41-52) cm H2O at 10 mL, 51 (44-55) cm H2O at 20 mL, 52 (45-56) cm H2O at 30 mL, and 52 (45-55) cm H2O at 40 mL. The increase in regurgitation pressure with increasing cuff volume from 0 to 10 mL was statistically significant (P < 0.0001). Regurgitation pressure was higher for the LMA groups at all cuff volumes compared with the control group (P < 0.0001). There were no differences in regurgitation pressure among the LMA groups. We conclude that the correctly placed LMA and FLMA attenuate liquid flow between the esophagus and pharynx.
We have shown, in cadavers, that the correctly placed standard and flexible laryngeal mask airways attenuate liquid flow between the pharynx and esophagus.
在这项随机对照尸体研究中,我们检验了以下假设:标准喉罩气道(LMA)和可弯曲喉罩气道(FLMA)可减少食管与咽部之间的液体流动。对50具新鲜尸体进行了研究,分为4个LMA组。10具女性尸体使用4号LMA,10具使用4号FLMA;10具男性尸体使用5号LMA,10具使用5号FLMA;5具男性和5具女性尸体作为对照组。打开胸腔,将压力控制连续流泵的输液装置插入食管并结扎固定。食管压力以2 cmH₂O的增量增加。反流压力是指在对照组中,用纤维内镜在下咽首次看到液体时的食管压力,以及在LMA组中,在套囊上方或碗内首次看到液体时的食管压力。在LMA组中,套囊容积从0至40 mL,以10 mL的增量进行此项操作。对照组的平均(95%置信区间)反流压力在套囊容积为0 mL时为7(6 - 8)cmH₂O,LMA组合并后的反流压力在套囊容积为0 mL时为19(17 - 20)cmH₂O,10 mL时为47(41 - 52)cmH₂O,20 mL时为51(44 - 55)cmH₂O,30 mL时为52(45 - 56)cmH₂O,40 mL时为52(45 - 55)cmH₂O。套囊容积从0增加到10 mL时,反流压力的增加具有统计学意义(P < 0.0001)。在所有套囊容积下,LMA组的反流压力均高于对照组(P < 0.0001)。LMA组之间的反流压力没有差异。我们得出结论,正确放置的LMA和FLMA可减少食管与咽部之间的液体流动。
我们在尸体研究中表明,正确放置的标准和可弯曲喉罩气道可减少咽部与食管之间的液体流动。