Filippi M, Rovaris M, Pereira C, Comi G
Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan, Italy.
Magn Reson Imaging. 1999 Apr;17(3):457-8. doi: 10.1016/s0730-725x(98)00202-1.
In this longitudinal study, we evaluated the sensitivities of dual-echo, conventional spin-echo (CSE), and rapid-acquisition relaxation-enhanced (RARE) scans for detecting the appearance of new lesions in multiple sclerosis (MS). Dual echo, CSE, and RARE scans were obtained on four occasions each separated by 28 days from five patients with relapsing-remitting MS using a 1.5-Tesla machine. A total of 44 new lesions were detected by the two sequences. Thirty-five lesions were seen on both sequences, three only on CSE and six only on FSE. This study indicates that CSE may be substituted by RARE when monitoring short-term disease activity in MS.
在这项纵向研究中，我们评估了双回波、传统自旋回波（CSE）和快速采集弛豫增强（RARE）扫描对检测多发性硬化症（MS）新病灶出现的敏感性。使用1.5特斯拉机器，对5例复发缓解型MS患者每隔28天进行一次双回波、CSE和RARE扫描，共进行4次。两个序列共检测到44个新病灶。两个序列均发现35个病灶，CSE单独发现3个，快速自旋回波（FSE）单独发现6个。本研究表明，在监测MS短期疾病活动时，RARE可替代CSE。
