Callesen T, Bech K, Andersen J, Nielsen R, Roikjaer O, Kehlet H
Department of Surgical Gastroenterology, Copenhagen University Hospital, Denmark.
J Am Coll Surg. 1999 Apr;188(4):355-9. doi: 10.1016/s1072-7515(98)00316-0.
Pain is an important problem after ambulatory hernia repair. To assess the influence of the surgical technique on postoperative pain, two separate randomized, patient-blinded, controlled trials were performed in men with an indirect inguinal hernia.
In study A, 48 patients with an internal inguinal ring smaller than 1.5 cm were randomly allocated to either simple extirpation of the hernial sac or extirpation plus annulorrhaphy. In study B, 84 patients with an internal inguinal ring wider than 1.5 cm were randomly allocated to extirpation plus annulorrhaphy or extirpation plus Lichtenstein mesh repair (modified). All operations were performed under unmonitored local anesthesia with standardized perioperative analgesia using methadone and tenoxicam. Pain was scored daily for the first postoperative week and after 4 weeks on a four-point verbal-rank scale (no, light, moderate, or severe pain) during rest, while coughing, and during mobilization (rising to the sitting position). Use of supplementary analgesics (paracetamol) was recorded. Cumulative daily pain scores for the first postoperative week and the number of patients who used supplementary analgesics were the main outcome measures.
There were no significant differences in cumulative pain scores or use of supplementary analgesics between the treatment groups in either study. Cumulative pain scores were significantly higher during coughing and mobilization than during rest in both studies.
Choice of surgical technique for open repair of a primary indirect inguinal hernia has no influence on postoperative pain.
门诊疝气修补术后疼痛是一个重要问题。为评估手术技术对术后疼痛的影响,对患有腹股沟斜疝的男性患者进行了两项独立的随机、患者盲法对照试验。
在研究A中,48例腹股沟内环小于1.5厘米的患者被随机分配至单纯疝囊切除组或疝囊切除加内环修补组。在研究B中,84例腹股沟内环大于1.5厘米的患者被随机分配至疝囊切除加内环修补组或疝囊切除加改良Lichtenstein修补组。所有手术均在未监测的局部麻醉下进行,围手术期使用美沙酮和替诺昔康进行标准化镇痛。术后第一周每天以及术后4周时,在休息、咳嗽和活动(坐起)时,采用四点语言等级量表(无、轻度、中度或重度疼痛)对疼痛进行评分。记录补充镇痛药(对乙酰氨基酚)的使用情况。术后第一周的每日累积疼痛评分以及使用补充镇痛药的患者数量为主要观察指标。
两项研究中,治疗组之间在累积疼痛评分或补充镇痛药使用方面均无显著差异。两项研究中,咳嗽和活动时的累积疼痛评分均显著高于休息时。
原发性腹股沟斜疝开放修补术的手术技术选择对术后疼痛无影响。