Pless J
Scand J Plast Reconstr Surg. 1976;10(2):147-51. doi: 10.3109/02844317609105202.
An analysis of 246 operated patients with 260 carcinomas of the external ears from the periods 1949-57 and 1962-67 is presented. Carcinoma of the external ear occurs in Denmark with a frequency of 1.2 cases per 100 000 inhabitants and constitutes approximately 6% of all skin cancers. In the present material 67% of the tumours were squamous-cell carcinomas and 30% were basal-cell carcinomas. These forms of tumours were most frequent in elderly men who have had outdoor employment. Half of these tumours were sited on the helix and lobe, while one quarter, respectively, were sited medially and laterally. 15% of the squamous-cell carcinomas recurred, 3% of the these with metastases of the regional lymph nodes. Of the basal-cell carcinomas 18% recurred but with no metastases of the regional lymph nodes. The frequency of recurrence did not depend on the site of the tumour on the ear, but it did increase with increasing tumour size. The 5-year survival rate without recurrence was 56% +/- 4% for the squamous-cell carcinomas, and for the basal-cell carcinomas 59% +/- 6.5%. It is concluded that surgical treatment is best suited for these tumours, and the minimum excision distance for basal-cell carcinomas of less than 3 cm in size should be 8 mm, while for squamous-cell carcinomas of the same size the distance should be 10 mm. For both forms of tumour where the greatest extent is more than 3 cm the excision distance should be at least 15 mm.
本文对1949 - 1957年以及1962 - 1967年间246例接受手术治疗的260例外耳道癌患者进行了分析。丹麦外耳道癌的发病率为每10万居民中有1.2例,约占所有皮肤癌的6%。在本研究资料中,67%的肿瘤为鳞状细胞癌,30%为基底细胞癌。这些肿瘤类型在从事户外工作的老年男性中最为常见。一半的肿瘤位于耳轮和耳垂,而分别有四分之一位于内侧和外侧。15%的鳞状细胞癌复发,其中3%伴有区域淋巴结转移。基底细胞癌的复发率为18%,但无区域淋巴结转移。复发频率并不取决于肿瘤在耳部的位置,但会随着肿瘤大小的增加而升高。鳞状细胞癌无复发的5年生存率为56%±4%,基底细胞癌为%59±6.5%。结论是手术治疗最适合这些肿瘤,对于大小小于3 cm的基底细胞癌,最小切除距离应为8 mm,而对于相同大小的鳞状细胞癌,距离应为10 mm。对于两种最大范围超过3 cm的肿瘤,切除距离应至少为15 mm。