Tomizawa K, He X, Yamanaka H, Shiosaka S, Yoshida S
Division of Structural Cell Biology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.
Brain Res. 1999 Apr 10;824(2):308-11. doi: 10.1016/s0006-8993(99)01238-x.
We have shown that neuropsin is expressed in the neurons of the limbic system in the adult mouse. After the central nervous system was injured by incision or intraperitoneal kainate injection, neuropsin mRNA was induced in the peri-lesioned region. The cells in which neuropsin mRNA was induced were localized mainly in axon fiber pathways and closely associated to proteolipid protein (PLP) mRNA expressing oligodendrocytes.
我们已经表明，在成年小鼠的边缘系统神经元中表达了神经蛋白酶。在通过切割或腹腔注射海藻酸损伤中枢神经系统后，在损伤周围区域诱导了神经蛋白酶mRNA的表达。诱导神经蛋白酶mRNA的细胞主要定位于轴突纤维通路中，并与表达蛋白脂质蛋白（PLP）mRNA的少突胶质细胞密切相关。
