Lacefield W R
Biomaterials Department, University of Alabama at Birmingham, USA.
Implant Dent. 1998;7(4):315-22. doi: 10.1097/00008505-199807040-00010.
There are various ceramic coatings available for dental implants. From a commercial standpoint, plasma-sprayed hydroxyapatite (HA) is the most popular. These coatings are typically partially amorphous after processing and contain crystalline phases other than HA. Plasma-sprayed HA and the other bioactive ceramic coating materials have been shown to enhance bone apposition as compared with uncoated metal implants. Some of the other available materials include the bioglasses, other calcium phosphates such as fluorapatite and tricalcium phosphate, and the inert ceramics such as alumina. The plasma-spray process is not optimum for all types of ceramic coatings, because it is not suitable for coating porous surfaces; the exact control of structure and chemistry is difficult with this process, and bond strength is not as high as is desired for some applications. Alternative methods for coating include sol-gel processing, ion beam and radio frequency (RF) sputtering, pulsed laser deposition, hot isostatic pressing, and electrophoretic deposition. The use of osteoinductive agents in conjunction with ceramic-coated implants is of current interest, and the degree and type of bonding of these agents appear to vary with the composition of the ceramic coating. Because there seems to be no satisfactory means of incorporating osteoinductive agents into ceramic coatings during any of the conventional coating procedures, the best approach seems to be to diffuse the agents into the coating after processing. Other possibilities include the tethering of the agents to the surface of the ceramic by suitable organic molecules or the placing of the agent in some carrier material such as a cement, which is placed around the implants.
有多种陶瓷涂层可用于牙种植体。从商业角度来看,等离子喷涂羟基磷灰石(HA)是最受欢迎的。这些涂层在加工后通常部分为非晶态,并且含有除HA之外的晶相。与未涂层的金属种植体相比,等离子喷涂HA和其他生物活性陶瓷涂层材料已被证明可增强骨附着。其他一些可用材料包括生物玻璃、其他磷酸钙如氟磷灰石和磷酸三钙,以及惰性陶瓷如氧化铝。等离子喷涂工艺并非适用于所有类型的陶瓷涂层,因为它不适用于涂覆多孔表面;此工艺难以精确控制结构和化学组成,并且结合强度对于某些应用来说不如预期的高。涂层的替代方法包括溶胶 - 凝胶工艺、离子束和射频(RF)溅射、脉冲激光沉积、热等静压和电泳沉积。将骨诱导剂与陶瓷涂层种植体结合使用是当前感兴趣的领域,并且这些试剂的结合程度和类型似乎随陶瓷涂层的组成而变化。由于在任何传统涂层工艺中似乎都没有令人满意的方法将骨诱导剂掺入陶瓷涂层中,最佳方法似乎是在加工后将试剂扩散到涂层中。其他可能性包括通过合适的有机分子将试剂 tethering 到陶瓷表面,或者将试剂放置在某些载体材料如水泥中,然后将其放置在种植体周围。 (注:“tethering”这个词在文中可能有误,推测可能是“附着”之类的意思,但按要求保留原文。)