Allen K B, Faber L P, Warren W H, Shaar C J
Department of Cardiovascular and Thoracic Surgery, Rush-Presbyterian-St. Lukes Medical Center, Chicago, Illinois, USA.
Ann Thorac Surg. 1999 Feb;67(2):437-40. doi: 10.1016/s0003-4975(98)01192-8.
Optimal management of cardiac tamponade resulting from pericardial effusion remains controversial.
Cardiac tamponade in 117 patients was treated with either subxiphoid pericardiostomy (n = 94) or percutaneous catheter drainage (n = 23). Percutaneous catheter drainage was used for patients with hemodynamic instability that precluded subxiphoid pericardiostomy. Effusions were malignant in 75 (64%) of 117 patients and benign in 42 (36%) of 117.
Subxiphoid pericardiostomy had no operative deaths and a complication rate of 1.1% (1 of 94). In contrast, percutaneous drainage had significantly (p < 0.05) higher mortality and complication rates of 4% (1 of 23) and 17% (4 of 23), respectively. Patients with an underlying malignancy had a median survival of 2.2 months, with a 1-year actuarial survival rate of 13.8%. In comparison, patients with benign disease had a median survival of 42.8 months and a 1-, 2-, and 4-year actuarial survival rate of 79%, 73%, and 49%, respectively (p < 0.05). Effusions recurred in 1 (1.1%) of 94 patients after subxiphoid pericardiostomy compared with 7 (30.4%) of 23 patients with percutaneous drainage (p < 0.0001).
Benign and malignant pericardial tamponade can be safely and effectively managed with subxiphoid pericardiostomy. Percutaneous catheter drainage should be reserved for patients with hemodynamic instability.
因心包积液导致的心包填塞的最佳治疗方法仍存在争议。
117例心包填塞患者接受了剑突下心包造口术(n = 94)或经皮导管引流术(n = 23)治疗。经皮导管引流术用于血流动力学不稳定、无法进行剑突下心包造口术的患者。117例患者中75例(64%)的积液为恶性,42例(36%)为良性。
剑突下心包造口术无手术死亡病例,并发症发生率为1.1%(94例中的1例)。相比之下,经皮引流的死亡率和并发症发生率显著更高(p < 0.05),分别为4%(23例中的1例)和17%(23例中的4例)。患有潜在恶性肿瘤的患者中位生存期为2.2个月,1年精算生存率为13.8%。相比之下,患有良性疾病患者的中位生存期为42.8个月,1年、2年和4年精算生存率分别为79%、73%和49%(p < 0.05)。剑突下心包造口术后94例患者中有1例(1.1%)积液复发,而经皮引流的23例患者中有7例(30.4%)复发(p < 0.0001)。
剑突下心包造口术可安全有效地治疗良性和恶性心包填塞。经皮导管引流术应仅用于血流动力学不稳定的患者。