Novitskiĭ V V, Stepovaia E A, Bazhenova N G, Gol'dberg V E, Kolosova M V, Saprykina E V, Sokolova I B, Koreshkova K G, Bulavina Ia V
Institute of Pharmacology, Tomsk Research Center, Siberian Branch, Russian Academy of Medical Sciences, Russia.
Eksp Klin Farmakol. 1999 Jan-Feb;62(1):56-9.
The lipid spectrum of erythrocyte membranes was studied by thin-layer and gas-liquid chromatography in patients with lung cancer in the process of antineoplastic cytostatic chemotherapy. The control group of examined subjects was formed of healthy volunteers. During a course of antineoplastic polychemotherapy according to the CAM scheme (cyclophosphan, adriamycin, methotrexate) disorders of the erythrocyte membrane lipid spectrum in patients with II-IV stage lung cancer remained or became still more manifest.
采用薄层色谱法和气液色谱法，对肺癌患者在进行抗肿瘤细胞抑制化疗过程中红细胞膜的脂质谱进行了研究。对照组由健康志愿者组成。在按照CAM方案（环磷酰胺、阿霉素、甲氨蝶呤）进行抗肿瘤联合化疗的过程中，Ⅱ - Ⅳ期肺癌患者红细胞膜脂质谱的紊乱依然存在或变得更加明显。
