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[多药化疗期间不同类型适应反应的肺癌患者的细胞免疫参数]

[Parameters of cellular immunity in lung cancer patients with different types of adaptation reactions during polychemotherapy].

作者信息

Stakheeva M N, Dizer I A, Smol'ianinov E S, Goldberg V E, Novitskiĭ E V, Sherstoboev E Iu, Khlusova M Iu

机构信息

Research Institute of Pharmacology, Russian Academy of Medical Sciences, Tomsk.

出版信息

Vopr Onkol. 1998;44(2):164-6.

PMID:9615819
Abstract

A relationship between cellular immunity and general adaptation syndrome in the course of CAM polychemotherapy has been investigated. The results point to a lack of lymphopenia, lower levels of T-suppressors and higher instability of immunological indices in patients showing increased activation reaction and maximum antitumor resistance during cytostatic therapy, unlike in those in stress. This opens an opportunity for correction.

摘要

研究了细胞免疫与辅助多药化疗过程中全身适应综合征之间的关系。结果表明,与处于应激状态的患者不同,在细胞毒性治疗期间表现出激活反应增强和最大抗肿瘤抵抗力的患者不存在淋巴细胞减少,T抑制细胞水平较低,免疫指标的不稳定性较高。这为进行纠正提供了契机。

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