Hurko O, Provost T T
Neuroscience Research, SmithKline Beecham Pharmaceuticals, Harlow, Essex, UK.
J Neurol Neurosurg Psychiatry. 1999 Apr;66(4):417-30. doi: 10.1136/jnnp.66.4.417.
As knowledge of pathophysiology grows, so does the refinement of diagnoses. Sometimes increased knowledge permits consolidation and unification. Unfortunately, at our present level of understanding, it usually demands proliferation of diagnostic categories. As tedious as this diagnostic splintering may seem, such is the price currently exacted of both the investigator and the clinician who seek to optimise management. Increased diagnostic refinement often requires inquiry into matters outside the bounds of one's specialty. Most often we turn to the radiologist or to the laboratory to narrow the differential diagnosis generated from the history and neurological examination. As we have shown, a useful intermediate step is extension of the physical examination to organs such as the skin, which are not the traditional preserve of the neurologist. That any text could confer the sophistication required for expert dermatological diagnosis is an unrealistic expectation. However, we hope that this review will encourage careful examination of the skin, hair, and nails by the neurological practitioner, with consideration of referral to a dermatologist when greater expertise is required.
随着病理生理学知识的增长,诊断也日益精细化。有时知识的增加会促成诊断的整合与统一。不幸的是,就我们目前的理解水平而言,这通常需要增加诊断类别。尽管这种诊断的细化看似繁琐,但这是目前寻求优化治疗的研究者和临床医生所要付出的代价。诊断的进一步细化往往需要探究超出自身专业范围的问题。大多数情况下,我们会求助于放射科医生或实验室,以缩小根据病史和神经系统检查得出的鉴别诊断范围。正如我们所表明的,一个有用的中间步骤是将体格检查扩展到诸如皮肤等器官,而皮肤并非神经科医生的传统检查范畴。指望任何文本都能提供专家级皮肤诊断所需的专业知识是不切实际的期望。然而,我们希望这篇综述能鼓励神经科从业者仔细检查皮肤、毛发和指甲,在需要更高专业知识时考虑转诊给皮肤科医生。