Burg G, Burg D
Dermatologische Klinik und Poliklinik, Universitätsspital Zürich.
Ther Umsch. 1995 Apr;52(4):243-50.
The considerable variety of diseases involving both the skin and the peripheral or central nervous system is due to the developmental relationship between skin and nervous system. Diseases of the nervous system resulting in skin changes comprise disorders of nails, hair, sweat and sebaceous glands as well as neuropathic ulcers in various manifestations. Neurocutaneous syndromes (phacomatoses) are nevoid systemic diseases comprising neurofibromatoses, tuberose sclerosis, ataxia telangiectasia, nevoid angiomatoses and other neurocutaneous disorders. Polytopic disorders of the skin and nervous system may be due to infectious diseases, diseases of the connective tissue, fat, inflammatory vascular and granulomatous disorders.
涉及皮肤与周围或中枢神经系统的疾病种类繁多，这是由于皮肤与神经系统之间的发育关系所致。导致皮肤变化的神经系统疾病包括指甲、毛发、汗腺和皮脂腺的疾病以及各种表现形式的神经性溃疡。神经皮肤综合征（phacomatoses）是一类痣样全身性疾病，包括神经纤维瘤病、结节性硬化症、共济失调毛细血管扩张症、痣样血管瘤病和其他神经皮肤疾病。皮肤和神经系统的多部位疾病可能由传染病、结缔组织疾病、脂肪疾病、炎症性血管疾病和肉芽肿性疾病引起。
