van der Putten J J, Hobart J C, Freeman J A, Thompson A J
Institute of Neurology, London, UK.
J Neurol Neurosurg Psychiatry. 1999 Apr;66(4):480-4. doi: 10.1136/jnnp.66.4.480.
The importance of evaluating disability outcome measures is well recognised. The Functional Independence Measure (FIM) was developed to be a more comprehensive and "sensitive" measure of disability than the Barthel Index (BI). Although the FIM is widely used and has been shown to be reliable and valid, there is limited information about its responsiveness, particularly in comparison with the BI. This study compares the appropriateness and responsiveness of these two disability measures in patients with multiple sclerosis and stroke.
Patients with multiple sclerosis (n=201) and poststroke (n=82) patients undergoing inpatient neurorehabilitation were studied. Admission and discharge scores were generated for the BI and the three scales of the FIM (total, motor, and cognitive). Appropriateness of the measures to the study samples was determined by examining score distributions, floor and ceiling effects. Responsiveness was determined using an effect size calculation.
The BI, FIM total, and FIM motor scales show good variability and have small floor and ceiling effects in the study samples. The FIM cognitive scale showed a notable ceiling effect in patients with multiple sclerosis. Comparable effect sizes were found for the BI, and two FIM scales (total and motor) in both patients with multiple sclerosis and stroke patients.
All measures were appropriate to the study sample. The FIM cognitive scale, however, has limited usefulness as an outcome measure in progressive multiple sclerosis. The BI, FIM total, and FIM motor scales show similar responsiveness, suggesting that both the FIM total and FIM motor scales have no advantage over the BI in evaluating change.
评估残疾结局指标的重要性已得到广泛认可。功能独立性测量(FIM)的开发目的是成为一种比巴氏指数(BI)更全面、更“敏感”的残疾测量方法。尽管FIM被广泛使用且已被证明具有可靠性和有效性,但关于其反应性的信息有限,尤其是与BI相比。本研究比较了这两种残疾测量方法在多发性硬化症和中风患者中的适用性和反应性。
对201例多发性硬化症患者和82例接受住院神经康复治疗的中风后患者进行了研究。生成了BI和FIM三个量表(总分、运动和认知)的入院和出院评分。通过检查评分分布、地板效应和天花板效应来确定测量方法对研究样本的适用性。使用效应量计算来确定反应性。
BI、FIM总分和FIM运动量表在研究样本中显示出良好的变异性,地板效应和天花板效应较小。FIM认知量表在多发性硬化症患者中显示出明显的天花板效应。在多发性硬化症患者和中风患者中,BI以及两个FIM量表(总分和运动)的效应量相当。
所有测量方法都适用于研究样本。然而,FIM认知量表作为进展性多发性硬化症的结局指标,其有用性有限。BI、FIM总分和FIM运动量表显示出相似的反应性,这表明在评估变化方面,FIM总分和FIM运动量表相对于BI没有优势。