Yu S C, Lee Y L, Metreweli C
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, Hong Kong.
Clin Radiol. 1999 Mar;54(3):176-8. doi: 10.1016/s0009-9260(99)91010-3.
Advancement of radiologic technologies allows the detection of vertebral lesions at an earlier stage, thereby increasing the proportion of vertebral lesions that are surrounded by intact bone when they are detected. While biopsy guns are effective in obtaining good-quality tissue samples of osteolytic bone lesions, lesions that are covered by intact bone are not accessible with a biopsy gun. For percutaneous biopsy of osteolytic vertebral lesions, an intact-bone transgressing technique is described in which a simple, inexpensive and small-calibre (18-gauge) instrument is used to allow multiple passage of 20-gauge biopsy guns for effective tissue sampling. In this series consisting of metastatic and myeloproliferative lesions, the effectiveness and safety of this well-tolerated technique are demonstrated in thoracic and lumbar vertebrae.
放射技术的进步使得能够在更早阶段检测到椎体病变，从而增加了检测到的被完整骨质包围的椎体病变的比例。虽然活检枪在获取溶骨性骨病变的高质量组织样本方面很有效，但被完整骨质覆盖的病变无法用活检枪获取样本。对于溶骨性椎体病变的经皮活检，本文描述了一种突破完整骨质的技术，其中使用一种简单、廉价且小口径（18号）的器械，以便20号活检枪能够多次通过，从而有效地获取组织样本。在这个由转移性和骨髓增殖性病变组成的系列研究中，该耐受性良好的技术在胸椎和腰椎中的有效性和安全性得到了证实。
