Fleischhacker M, Beinert T
Medizinische Klinik m.S., Hämatologie und Onkologie, Charité, Campus Mitte, Schumannstr. 20/21, D-10117 Berlin, Germany.
Eur J Med Res. 1999 Apr 27;4(4):144-8.
The knowledge about the molecular genetic features of cancer has been vastly increased within the last few years. Tumor markers used so far for diagnosis, monitoring, and follow-up of cancer patients are tumor-associated rather than tumor-specific. Therefore, the development of more sensitive and specific tumor markers is urgently needed. In this review, the possibilities of using molecular genetic characteristics of cancer as specific and sensitive tumor markers are discussed.
在过去几年中，关于癌症分子遗传特征的知识有了极大的增长。迄今为止用于癌症患者诊断、监测和随访的肿瘤标志物是肿瘤相关的，而非肿瘤特异性的。因此，迫切需要开发更敏感、更特异的肿瘤标志物。在这篇综述中，我们讨论了将癌症的分子遗传特征用作特异性和敏感性肿瘤标志物的可能性。
