Sharma R K, Wang Y, Falcone T, Goldberg J, Agarwal A
Department of Urology, Cleveland Clinic Foundation, Ohio, USA.
Int J Fertil Womens Med. 1999 Jan-Feb;44(1):31-7.
To determine whether peritoneal fluid from women with endometriosis contributes to infertility by impairing sperm motion and functional characteristics.
Women with endometriosis (n = 20) underwent laparoscopy for infertility or pelvic pain. Patients undergoing tubal ligation served as controls (n = 14). Peritoneal fluid was aspirated from women with endometriosis, or from women undergoing laparoscopic tubal ligation. Sperm motility, motion characteristics and acrosome reaction were assessed following incubation with peritoneal fluid.
Sperm motility, motion characteristics, and acrosome reaction did not differ significantly between the two groups after 3, 5, or 24 hours of incubation with peritoneal fluid.
Sperm motion or functional characteristics showed no significant impairment when sperm from normal donors were incubated with peritoneal fluid from patients with endometriosis. It is unlikely that peritoneal fluid in these patients contributes to infertility.
确定子宫内膜异位症女性的腹腔液是否通过损害精子运动和功能特征而导致不孕。
患有子宫内膜异位症的女性（n = 20）因不孕或盆腔疼痛接受腹腔镜检查。接受输卵管结扎的患者作为对照（n = 14）。从患有子宫内膜异位症的女性或接受腹腔镜输卵管结扎的女性中抽取腹腔液。在与腹腔液孵育后评估精子活力、运动特征和顶体反应。
与腹腔液孵育3、5或24小时后，两组之间的精子活力、运动特征和顶体反应没有显著差异。
当正常供体的精子与子宫内膜异位症患者的腹腔液孵育时，精子运动或功能特征没有显著受损。这些患者的腹腔液不太可能导致不孕。
Zotero 插件