Canales E S, Del Rocío Cruz P, Montoya R
Departamento de Biología de la Reproducción y Gineco-Endocrinología,Hospital de Gineco-Obstetricia Centro Médico La Raza, IMSS. México, D.F.
Ginecol Obstet Mex. 1991 Mar;59:93-6.
Recently, there has been information about the ultrafiltrated peritoneal fluid in patients with endometriosis, containing macromollecules that diminish tubal fimbria action, and the in vitro ovular captation in experimental animals. In order to investigate the presence of these substances in the peritoneal fluid, and to know the possible effect that could have on spermatic motivility in vitro, of their mates; 11 sterile women with diagnosis of pelvic endometriosis, and 11 normal fertile women, were studied. On the other side, the same day of study, the mate of each of these women, produced semen obtained by masturbation, where amount and motility of sperm, in basal conditions, and after, it was capacitated with Ham-F10, were determined. The final results was evaluated as to percentage of spermatozoon with excellent and progressive motility, and percentage of motionless spermatozoo as well as based on average values (mean +/- EE), of each one of them. The statistic analysis of differences was done by t Student that in coupled samples. The results confirm that peritoneal fluid of patient with endometriosis contains macromollecules, and it shows that these substances affect the motility in vitro of mate's spermatozoon, which could explain, partially at least, the origin of sterility in this disease.
最近,有关于子宫内膜异位症患者超滤腹膜液的信息,其中含有会削弱输卵管伞作用的大分子,以及实验动物的体外卵子捕获情况。为了研究这些物质在腹膜液中的存在情况,并了解其对伴侣精子体外活力可能产生的影响,对11名诊断为盆腔子宫内膜异位症的不育女性和11名正常可育女性进行了研究。另一方面,在研究当天,这些女性的伴侣通过手淫获取精液,测定基础状态下以及用Ham-F10使其获能后的精子数量和活力。最终结果根据具有优秀和进行性活力的精子百分比、不动精子百分比以及它们各自的平均值(均值±标准误)进行评估。差异的统计分析采用配对样本t检验。结果证实,子宫内膜异位症患者的腹膜液含有大分子,并且表明这些物质会影响伴侣精子的体外活力,这至少可以部分解释该疾病不育的原因。